What is this medication?

ACETOHYDROXAMIC ACID (as i to hi DROK sam ik AS id) treats urinary tract infections (UTIs) caused by bacteria that increase ammonia levels in your urine. It works by lowering ammonia levels in your urine. This slows the growth of kidney stones. It can also help antibiotics for UTIs work better.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

COMMON BRAND NAME(S): Lithostat

What should I tell my care team before I take this medication?

They need to know if you have any of these conditions:

• Kidney disease
• Low blood counts, like low white cell, platelet, or red cell counts
• An unusual or allergic reaction to acetohydroxamic acid, other medications, foods, dyes, or preservatives
• Pregnant or trying to get pregnant
• Breast-feeding

How should I use this medication?

Take this medication by mouth with a glass of water. Follow the directions on the prescription label. Take this medication on an empty stomach, at least 1 hour before or 2 hours after food. Do not take with food. Medications that contain iron should not be taken at the same time as this medication. Take your medication at regular intervals. Do not take it more often than directed. Do not stop taking except on your care team's advice.

A patient package insert for the product will be given with each prescription and refill. Read this sheet carefully each time. The sheet may change frequently.

Talk to your care team about the use of this medication in children. While this medication may be prescribed in children for selected conditions, precautions do apply.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medication?

This medication may interact with the following:

• Alcohol
• Iron
• Vitamin and mineral supplements containing iron

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medication?

Tell your care team if your symptoms do not start to get better or if they get worse.

Alcohol may cause a flushing skin reaction and other uncomfortable effects if taken with this medication. Avoid alcoholic drinks.

What side effects may I notice from receiving this medication?

Side effects that you should report to your care team as soon as possible:

• Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
• Low red blood cell level—unusual weakness or fatigue, dizziness, headache, trouble breathing

Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):

• Anxiety, nervousness
• Hair loss
• Headache
• Loss of appetite
• Nausea
• Tremors or shaking
• Upset stomach

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medication?

Keep out of the reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Throw away any unused medication after the expiration date.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.