What is this medication?

UNOPROSTONE (yoo noh PROST ohn) lowers the pressure in the eye. It is used to treat open-angle glaucoma and high pressure in the eye.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

COMMON BRAND NAME(S): Rescula

What should I tell my care team before I take this medication?

They need to know if you have, or have had any of these conditions:

•closed-angle glaucoma

•eye abrasion, infection, or inflammation

•kidney disease

•liver disease

•wear contact lenses

•an unusual or allergic reaction to unoprostone or other medicines, foods, dyes, or preservatives

•pregnant or trying to get pregnant

•breast-feeding

How should I use this medication?

This medicine is only for use in the eye. Do not take by mouth. Follow the directions on the prescription label. Wash hands before and after use. Tilt the head back slightly and pull down the lower lid with the index finger to form a pouch. Try not to touch the tip of the dropper to your eye or any other surface. Squeeze the prescribed number of drops into the pouch. Close the eye gently. Do not blink. Use your medicine at regular intervals. Do not use your medicine more often than directed.

If you are to administer other eye medications, they should be used at least 5 minutes apart from this medication.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, use it as soon as you can. If it is almost time for your next dose, use only that dose. Do not use double or extra doses.

What may interact with this medication?

Interactions are not expected. Do not use any other eye products without asking your doctor or health care professional.

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medication?

Visit your doctor or health care professional for regular checks on your progress. Report any serious side effects promptly. Stop using this medicine if your eyes get swollen, reddened (including 'pink eye' or conjunctivitis), painful, or have a discharge, and see your doctor or health care professional right away.

This medicine may cause your eye, eyelashes, and eyelids to darken or change color (brown). Tell your doctor or health care professional if this happens. These changes may be permanent.

If you develop an eye infection or injury, or have eye surgery scheduled, tell your health care professional that you use this product.

If you wear contact lenses, take them out before putting these drops in the eye. Wait at least 15 minutes after using the drops before putting your lenses back in.

Be careful not to touch the tip of the dispensing container onto the eye, or any other surface. Serious eye infections can result from contamination of eye solutions.

Wear dark glasses if this medicine makes your eyes more sensitive to light.

What side effects may I notice from receiving this medication?

Side effects that you should report to your doctor or health care professional as soon as possible:

•allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

•blurred vision or other changes in vision

•inflamed, swollen, painful, or infected eyes or eyelids

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

•burning, stinging, itching, or minor discomfort of the eyes or eyelids

•changes in the color of the eye(s) (increase in brown color), or darkening of the eyelashes or eyelid(s)

•dry eyes or the feeling of something in the eye

•increased flow of tears

•increased sensitivity of the eyes to light

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medication?

Keep out of reach of children.

Store between 2 and 25 degrees C (36 and 77 degrees F). Throw away any unused medication after the expiration date.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.